Published in Gene Therapy Weekly, September 27th, 1999
It has been noted that the M. tuberculosis KatG enzyme, like most hydroperoxidase 1 (HP1)-type catalases, consists of two related domains, each with strong similarity to the yeast cytochrome c peroxidase.
"The catalase-peroxidase activity is associated with the amino-terminal domain but currently no definite function has been assigned to the carboxy-terminal domain, although it may play a role in substrate binding," researcher M.A. Mulder and colleagues wrote ("Involvement of the N- and C-Terminal Domains of Mycobacterium...
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Source: Gene Therapy Weekly (1999-09-27)
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