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Gene Sequencing

Novel Mitochondrial DNA-Like Sequence Identified

Published in Gene Therapy Weekly, October 11th, 1999

A novel mitochondrial DNA-like sequence in the human nuclear genome was reported by researchers from San Diego, California's Mitokor.

C. Herrnstadt and colleagues described a nuclear mitochondrial DNA-like sequence (numtDNA) that is nearly identical in sequence to a continuous 5842 bp segment of human mitochondrial DNA (mtDNA) that spans nucleotide positions 3914 to 9755.

"On the basis of evolutionary divergence among modern primates, this numtDNA molecule appears to represent mtDNA from a hominid ancestor that has been translocated to the nuclear genome during the recent evolution of humans," Herrnstadt et al. wrote.

"This...

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