Peripheral Neuropathy (Gene Delivery)

Herpes-Delivered Gene Could Provide Long-Term, Systemic Therapy

Published in Gene Therapy Weekly, November 8th, 1999

The successful clinical delivery of a therapeutic gene for peripheral neuropathy could treat this form of nerve damage experienced by millions of individuals as a result of disease or drug exposure.

In new studies of two different animal models, investigators from the University of Pittsburgh in Pennsylvania for the first time have shown that a modified herpesvirus shuttles a therapeutic gene not only to neurons that it typically enters, but also to non-neuronal cells and in turn provides an important long-term source of protein called nerve growth factor (NGF).

Furthermore, they found that the newly manufactured NGF enters the bloodstream, where...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Gene Therapy Weekly

Source: Gene Therapy Weekly (1999-11-08)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry