Published in Gene Therapy Weekly, November 8th, 1999
In new studies of two different animal models, investigators from the University of Pittsburgh in Pennsylvania for the first time have shown that a modified herpesvirus shuttles a therapeutic gene not only to neurons that it typically enters, but also to non-neuronal cells and in turn provides an important long-term source of protein called nerve growth factor (NGF).
Furthermore, they found that the newly manufactured NGF enters the bloodstream, where...
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