Heart Disease (Risk)

Apolipoprotein E Gene Variant Increases Risk

Published in Gene Therapy Weekly, November 15th, 1999

A gene already implicated in high cholesterol may pose yet another risk for heart disease, according to a study presented November 7, 1999, at the American Heart Association's Scientific Sessions held in Atlanta, Georgia.

Apolipoprotein E is a key protein involved in the transport and disposal of cholesterol in the body. Sitting on the surface of circulating blood-fat particles, apo E normally binds to liver cells, to help rid the body of cholesterol. There are three variants of apo E.

Lead investigator of the study, Angelo Scuteri, MD, PhD, of the U.S. National Institute of Aging in Baltimore, Maryland, says research suggests that one of the...

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Source: Gene Therapy Weekly (1999-11-15)

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