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Vector Development

CAR-Independent Gene Transfer Efficient Via Adenoviral Vector

Published in Gene Therapy Weekly, January 13th, 2000

Altering adenovirus (Ad) tropism expands the potential of adenoviral-mediated gene transfer, suggests research from the University of Alabama.

David T. Curiel, representing colleagues from the Gene Therapy Center at the University of Alabama, reported on the development and modification of adenoviral vectors for gene therapy at the conference Gene Therapy: Delivering the Medicines of the 21st Century, held November 7-9, 1999, in Washington, DC. The title of his presentation was "CAR-Independent Gene Transfer to Accomplish Efficient, and Specific Genetic Modification of Target Cells Via Adenoviral Vectors."

"Adenoviruses have been widely employed...

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