Published in Gene Therapy Weekly, February 10th, 2000
"The ability to carry out gene targeting in somatic stem cells while maintaining their stem cell characteristics would have important implications for gene therapy and for the analysis of gene function," stated J. M. Harris and colleagues from Hammersmith Hospital, Imperial College, England. "Using mouse myoblasts, we have explored this possibility by attempting to alter the promoter of a myosin heavy chain gene (MyHCIIB) characteristic of physiologically 'fast' muscle so as to force...
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