Lymphocyte Marking

Sustained Levels of Lymphocyte Marking Achieved

Published in Gene Therapy Weekly, March 9th, 2000

Sustained levels of lymphocyte marking may be therapeutic in a number of human gene therapy applications that require targeting of the lymphoid compartment, reported researchers from United States.

"We have used a murine retrovirus vector containing an enhanced green fluorescent protein complimentary DNA (EGFP cDNA) to dynamically follow vector-expressing cells in the peripheral blood (PB) of transplanted rhesus macaques," stated R.E. Donahue and colleagues, NHLBI, Hematology Branch, Maryland, USA.

Donahue et al. published the results of their study in the journal Blood ("High levels of lymphoid expression of enhanced green fluorescent protein...

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Source: Gene Therapy Weekly (2000-03-09)

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