Thrombosis Therapy

TFPI Gene Transfer Can Prevent Arterial Thrombosis

Published in Gene Therapy Weekly, March 23rd, 2000

Thromboresistance can be instilled in balloon-injured porcine carotid arteries after local gene transfer of human tissue factor pathway inhibitor, reported researchers from the United States.

"Tissue factor pathway inhibitor (TFPI) is an endogenous inhibitor of factor Xa and the coagulant initiator complex tissue factor/factor VIIa," stated P. Zoldhelyi and colleagues from the Texas Heart Institute, Texas, USA. "We sought to study the effects of TFPI gene transfer on thrombus formation."

Zoldhelyi et al. published the results of their study in Circulation ("Thromboresistance of balloon-injured porcine carotid arteries after local gene...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Gene Therapy Weekly

Source: Gene Therapy Weekly (2000-03-23)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry