Vector Development

Improving Gene Therapy Delivery to Brain

Published in Gene Therapy Weekly, April 13th, 2000

After one injection, a certain gene vector can effectively reach many brain sites, according to University of Iowa and U.S. National Institutes of Health investigators.

They published their findings in the March 28, 2000, issue of the Proceedings of the National Academy of Sciences.

Developing successful gene therapy for neurodegenerative diseases that affect a large proportion of the brain is challenging. One hurdle involves ensuring that the gene vectors (disabled viruses that carry the genes ) are well distributed in the brain and efficiently deposit the genes in the target cells. However, University of Iowa and NIH investigators have...

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Source: Gene Therapy Weekly (2000-04-13)

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