Heart Transplantation

Ex vivo Gene Transfer Uses Hypothermic Perfusion of Vector

Published in Gene Therapy Weekly, May 4th, 2000

Highly efficient ex vivo gene transfer to the transplanted heart can be accomplished by hypothermic perfusion with a low dose of adenoviral vector, reported researchers from the United States.

"Hypothermic conditions required for donor heart preservation may reduce gene-transfer efficiency," stated C. Pellegrini and colleagues, Mayo Clinic & Mayo Foundation, Minnesota. "Experiments were designed to determine whether a perfusion technique could improve the efficiency of gene transfer to donor hearts."

Pellegrini et al. published the results of their study in the Journal of Thoracic and Cardiovascular Surgery ("Highly efficient ex vivo gene...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Gene Therapy Weekly

Source: Gene Therapy Weekly (2000-05-04)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry