Severe Combined Immunodeficiency Disease
Gene Therapy of Human (SCID)-X1 Reaches Clinical Trial
Published in Gene Therapy Weekly, June 15th, 2000
"SCID-X1 is an X-linked inherited disorder characterized by an early block in T and natural killer (NK) lymphocyte differentiation," wrote M. Cavazzana-Calvo and colleagues, Hopital Necker Enfants Maladaies, France. "This block is caused by mutations of the gene encoding the gamma c cytokine receptor subunit of interleukin-2, -4, -7, -9, and -15 receptors, which participates in the delivery of growth, survival, and differentiation signals to early lymphoid progenitors."
After successful preclinical studies,...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2000-06-15)
More Articles from Gene Therapy Weekly
- Cardiovascular Gene Therapy
Ex vivo Cardiomyoblast-Mediated Gene Transfer Successful - Vector Development
Receptor Molecule Facilitates Introduction of Corrected Genes into Cells - Antisense Therapy
Complete Reversal of Multidrug Resistance Phenotype Not Possible in Leukemia Cells - Arthritis Gene Therapy
Adeno-Associated Viral Vectors Ideal for in vivo Gene Therapy - Cancer Gene Therapy
Optimized Electroporation Shows Potential for Treatment of Gliomas - Mesothelioma
Gene Therapy-Based Approach May be Useful - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
