Published in Gene Therapy Weekly, June 29th, 2000
"New treatment methods are needed for head and neck cancer to improve survival without increasing morbidity," said L.L. Gleich and colleagues, University of Cincinnati, Ohio. "Gene therapy is a potential method of improving patient outcome. Given the current technological vector limitations in transmitting the therapeutic genes, treatments that require the fewest number of cells to be altered by the new gene are optimal. Therefore an immune-based gene therapy strategy was selected in which the tumors were transfected with the gene for an alloantigen, human leukocyte antigen...
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