Melanoma
Polynucleotide Vaccine from Melanoma Antigen Under Development
Published in Gene Therapy Weekly, July 27th, 2000
"MART-1, a melanoma antigen recognized by T cells-1, is a melanocyte lineage-differentiation antigen expressed only in melanocytes and melanoma cells," stated S.W. Lee and colleagues, University of Alabama. "This protein is recognized by many T-lymphocyte lines that are human leukocyte antigen (HLA)-A2 restricted and melanoma reactive. These observations have culminated in an array of clinical trials of MART-1 immunization using recombinant viruses or MART-1 immunodominant peptides."
Lee et al....
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Source: Gene Therapy Weekly (2000-07-27)
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