Published in Gene Therapy Weekly, August 10th, 2000
"In gene therapy for cancer, gene targeting of cancer cells is essential. HCC is a hypervascular tumor fed by tumor-specific arteries. The delivery of anticancer drugs through such arteries is known as transarterial embolism (TAE)," explained H. Shiba and colleagues from the Jikei University School of Medicine, Japan.
"We speculated that Lipiodol could be used to efficiently deliver a gene to HCC. However, Lipiodol could influence vector infection or transgene expression. ...
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