Autoimmune Disease

Naked DNA Vaccination May Conquer Arthritis and Multiple Sclerosis

Published in Gene Therapy Weekly, August 17th, 2000

A novel modification of a new technology born of genetic engineering, and known as naked DNA vaccination, holds the potential of overcoming autoimmune diseases such as multiple sclerosis and rheumatoid arthritis.

Under development by Dr. Nathan Karin of the Technion-Israel Institute of Technology, the vaccine is currently being successfully tested in animals. A paper on this technology appeared in the August 1, 2000, issue of the Journal of Clinical Investigation.

In multiple sclerosis (MS) and rheumatoid arthritis (RA), the body essentially attacks itself, causing inflammation. In MS, the myelin sheath of nerves falls victim, while in RA,...

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Source: Gene Therapy Weekly (2000-08-17)

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