Gene Delivery

New System Sidesteps Viruses

Published in Gene Therapy Weekly, September 7th, 2000

Gene therapy - which aims to replace "bad" genes with useful ones - has yet to live up to its promise largely because of problems delivering genes to the right place in the body.

What's more, the viruses many gene therapy techniques use can arouse unwanted immune reactions.

Researchers at Jefferson Medical College, Thomas Jefferson University, Pennsylvania, have developed a system that sidesteps viruses, and they hope, some of the inherent problems with their use. Scientists, led by Eric Wickstrom, PhD, professor of microbiology and immunology, and graduate research assistant Stephen H. Cleaver have used DNA and bacterial proteins to deliver a...

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Source: Gene Therapy Weekly (2000-09-07)

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