Published in Gene Therapy Weekly, September 14th, 2000
"Dendritic cells (DCs) are potent antigen-presenting cells (APCs), and are being intensively studied as promising vehicles for the specific induction of anti-tumor immunity," reported Frank G. Haluska and colleagues from the Massachusetts General Hospital, Dana-Farber Cancer Institute, and Genzyme Molecular Oncology, Massachusetts. "Our own preclinical murine studies demonstrate that genetic modification of DCs produce APCs highly efficient in the stimulation of immunity against tumor antigens."
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