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Human Papillomavirus

HPV16 Capsid Protein DNA Vaccine Induces Mucosal Immunity

Published in Gene Therapy Weekly, October 5th, 2000

Researchers in Poland and the United States collaborated on the development of a DNA-adenoviral recombinant vaccine regimen for the prevention of human papillomavirus (HPV) infection.

"Infection by certain subsets of HPV, most notably HPV types 16 and 18, has been implicated as the principal etiologic agents of cervical cancer," reported Dariusz W. Kowalczyk and colleagues from the Wistar Institute, Pennsylvania, and the Polish Academy of Sciences, Poland. "Thus development of effective vaccines to prevent or treat HPV infection could have a major impact on tumors caused by these viruses."

Kowalczyk et al. presented data from their study at the 14th...

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