Bladder Cancer
p53 Gene Transfer Chemosensitizes Tumor in vivo
Published in Gene Therapy Weekly, October 19th, 2000
H. Miyake and colleagues at Vancouver General Hospital conducted a study "to determine whether an adenovirus-mediated p53 gene (Ad5CMV-p53) transfer enhances cisplatin cytotoxicity in vitro and whether Ad5CMV-p53 and cisplatin synergistically inhibit growth and metastasis in vivo using human bladder cancer KoTCC-1 cells. MTT assays and DNA fragmentation assays were used to examine the effects of treatment with Ad5CMV-p53 and/or cisplatin on growth inhibition and induction of apoptosis, respectively, in KoTCC-1 cells."
The researchers...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2000-10-19)
More Articles from Gene Therapy Weekly
- HIV Gene Therapy
Antisense Enables Long-Term Survival of Transduced Immune Cells - Pancreatic Cancer
Sm-Like Oncogene is Novel Target for Gene Therapy - Animal Models
Immortomouse Hepatocytes Useful for Hepatic Gene Therapy Model - Cancer Gene Therapy
Scientists to Try Altering Gene Carrier to Improve its Ability to Bind to Cancer Cells - Lysosomal Storage Diseases
Intrahepatic Gene Therapy is Corrective in Murine Model - Prostate Cancer
p53 Adenovirus-Mediated Transfer Suppresses Primary Tumor Growth and Metastasis - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
