Prostate Cancer

p53 Adenovirus-Mediated Transfer Suppresses Primary Tumor Growth and Metastasis

Published in Gene Therapy Weekly, October 19th, 2000

Recent research from the United States showed that adenovirus-mediated p53 gene transfer suppressed primary tumor growth and progression to metastasis in animal models.

"Numerous advances have been made in gene therapy approaches for the treatment of solid tumors, including prostate cancer," wrote J.A. Eastham and colleagues, Louisiana State University. "While treatment of the primary tumor has been well investigated, little information is available regarding gene therapy techniques which might impact on the progression to metastatic disease. We investigate the ability of p53 adenovirus to suppress not only primary tumor growth, but also the progression...

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Source: Gene Therapy Weekly (2000-10-19)

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