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Vector Development

Company Reports Improved Transduction Efficacies with Replicative Vector Systems

Published in Gene Therapy Weekly, November 2nd, 2000

Avax Technologies, Inc. (AVXT) announced that David Klatzmann, MD presented data on the company's cancer gene therapy at the European Gene Therapy Conference in Stockholm, Sweden, earlier in October 2000.

The data reported were gathered from in vitro and in vivo studies and outline the improved transduction efficacy that can be achieved using replicative and semi-replicative vector systems compared to defective vectors. The results prompt careful reconsideration of using replicative viruses for treating cancer, Avax Technologies says.

The studies were supported by Pierre et Marie Curie University, Paris, France, and Centre National de la...

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