Cancer Therapies

Drug Shown to Preserve Ovarian Function in Mice

Published in Gene Therapy Weekly, November 2nd, 2000

For the first time, scientists have found a way to protect ovaries from the damage often caused by radiation and chemotherapy treatments for cancer.

Researchers at Memorial Sloan-Kettering Cancer Center, New York, along with colleagues from Massachusetts General Hospital and other institutions, have discovered that "knocking out" a particular gene protects the ovaries of mice from damage. Furthermore, knowledge of this genetic defect has led to a drug that - when injected into mouse ovaries before radiation treatments - preserves the ovaries' normal function, thus allowing them to continue producing eggs.

Early menopause and sterility are common...

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Source: Gene Therapy Weekly (2000-11-02)

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