Parkinson's Disease

Gene Therapy Rescues Brain Cells in PD Model

Published in Gene Therapy Weekly, November 9th, 2000

A gene therapy "cocktail" can successfully prevent the destruction of critical brain cells in an animal model of Parkinson's disease, according to a study presented at the American Neurological Association's 125th annual meeting, held October 15-18, 2000, in Boston, Massachusetts.

Researchers from the University of Tubingen in Germany reported that they were able to prevent the death of dopamine neurons, which are selectively destroyed in the disorder, by simultaneously interfering with "executioner" molecules called caspases and nourishing brain cells with molecules called growth factors.

"We combined neuroprotective and neurorestorative...

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Source: Gene Therapy Weekly (2000-11-09)

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