Published in Gene Therapy Weekly, December 21st, 2000
Researchers pursued the naked DNA injection approach to gene delivery because viral vectors of direct intra-articular gene therapy bring with them some inherent obstacles, such as variable host response to viral proteins as well as incorporation into host DNA, explained D.L. Boyle and colleagues in a presentation to the joint 64th annual scientific meeting of the American College of Rheumatology and the 35th annual meeting of the...
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