Published in Gene Therapy Weekly, January 18th, 2001
K. Inoue and colleagues at the University of Texas M.D. Anderson Cancer Center reported that in vitro, adenoviral-mediated antisense bFGF (Ad bFGF-AS) promotes endothelial cell apoptosis and inhibits reproduction of these cells. Their current experiment tested Ad bFGF-AS therapy in vivo in athymic nude mice. Transitional cell carcinoma (TCC) cell line 253J-BVR was implanted under the skin of the mice.
Inoue et al. reported their findings in the...
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