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AIDS Therapies

Cellular Fusion Inhibitors Show Promise

Published in Gene Therapy Weekly, February 1st, 2001

Recent research into the process of HIV cell fusion may lead to novel therapies for inhibiting or shutting down that process, researchers suggest in the journal Expert Opinion on Therapeutic Patents.

"Current anti-HIV therapies targeting reverse transcriptase and protease enzymes suffer from high cost, a high probability of engendering resistance, and adverse side effects following prolonged use," explained O.M.Z. Howard and colleagues at the U.S. National Cancer Institute in Maryland. "Thus, we are faced with the need to develop new antiviral strategies with more potent compounds and/or novel antiviral targets."

The success of other...

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