Liver Transplantation
Gene Therapy Improves Graft Function
Published in Gene Therapy Weekly, February 1st, 2001
"Oxygen-derived free radicals play a central role in reperfusion injury after organ transplantation, and fatty livers are particularly susceptible," stated T.G. Lehmann and colleagues, University of North Carolina. "Endogenous radical scavengers such as superoxide dismutase (SOD) degrade these radicals; however, SOD is destroyed rapidly when given exogenously. Therefore, an adenoviral vector encoding the Cu/Zn-SOD gene (Ad.SOD1) was used here to test the hypothesis that organ injury would be reduced and survival increased in a rat model of transplantation of fatty...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2001-02-01)
More Articles from Gene Therapy Weekly
- Cancer Gene Therapy
Radiotherapy Enhanced by Hyperthermia-Regulated Treatment - Cancer Gene Therapy
Novel Enzyme/Prodrug Combination for Suicide Protocols Developed - Cancer Gene Therapy
Targeted Gene Transfer into Soft Tissue Sarcomas Accomplished - Cancer Gene Therapy
Yeast Cytosine Deaminase Improves Radiosensitization and Bystander Effect - Cardiac Allograft Arteriopathy
Decoy Transfection Prevents Complication - Cord Blood
Understanding Developmental Changes Necessary for Future Use - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
