Parkinson's Disease
Neuroprotective Gene Therapy Evaluated in Rat Model
Published in Gene Therapy Weekly, February 22nd, 2001
"During the last few years, recombinant viral vectors derived from adenovirus (Ad), adeno-associated virus (AAV), or lentivirus (LV) have been developed into highly effective vehicles for gene transfer to the adult central nervous system," wrote A. Bjorklund and colleagues, University of Lund. "In recent experiments, in the rat model of Parkinson's disease, all three vector systems have been shown to be effective for long-term delivery of glial cell line-derived neurotrophic factor (GDNF) at biologically...
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Source: Gene Therapy Weekly (2001-02-22)
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