Immunology
CpG Motifs Have Therapeutic Potential
Published in Gene Therapy Weekly, March 8th, 2001
"The mammalian immune system has evolved mechanisms to recognize and respond to 'danger' signals arising from pathogens," said R.K. Scheule and colleagues at Genzyme. "Among those danger signals are the unmethylated CpG dinucleotide motifs found in bacteria."
According to the researchers, cytokines released by macrophages and related cells in response to CpG motifs are then responsible for activating other immune cells. These other immune cells, such as natural killer (NK) cells and T...
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Source: Gene Therapy Weekly (2001-03-08)
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