Published in Gene Therapy Weekly, June 28th, 2001
According to M. De Angioletti and colleagues, Memorial Sloan-Kettering Cancer Center, retrovirus vectors are beneficial in the treatment of heritable genetic disorders because they possess the capability for permanent transgene expression after integration into the host genome. Unfortunately, they warned, levels of transgene expression after insertion can vary widely as retroviral promoters are influenced by promoters and regulatory...
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