Published in Gene Therapy Weekly, July 5th, 2001
In the experimental mice, a circular defect in the distal metaphysis of the femur encompassed 20% of the circumference of the bone, which reduced bending 34% over control mice, explained Uusitalo and colleagues, University of Turku, Finland, in the journal Bone. This model was developed to observe the properties and characteristics of bone healing in vivo. It also has potential applications for gene therapy research in the area of bone regeneration.
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