Ischemia

Spontaneously Hypertensive Rats Respond to Kallikrein Gene Therapy

Published in Gene Therapy Weekly, August 16th, 2001

by Sonia Nichols, senior medical writer - Spontaneously hypertensive rats lack genes for growth factors that would promote angiogenesis in ischemic tissues, but kallikrein gene therapy can restore angiogenic responses and improve tissue healing in those animals.

This discovery, according to researchers in Italy at the National Laboratory of the National Institute of Biostructures and Biosystems (INBB), could be of value for developing novel treatments for individuals affected by reduced tissue revascularization after ischemic episodes.

The new research, reported in the July 2001 edition of Hypertension, compared angiogenic growth factor...

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Source: Gene Therapy Weekly (2001-08-16)

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