Published in Gene Therapy Weekly, August 23rd, 2001
"Reductions in cardiac sarcoplasmic reticulum calcium-ATPase (Serca2a) levels are thought to underlie the prolonged calcium (Ca2+) transients and consequent reduced contractile performance seen in human cardiac hypertrophy and heart failure," explained A.M. Reilly and colleagues, University of Melbourne, Australia.
They found evidence of this when examining freshly isolated rat cardiac myocytes after inducing right ventricular...
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