Alcoholism

Gene Therapy Reduces Drinking In Addicted Rats

Published in Gene Therapy Weekly, September 20th, 2001

Scientists at the U.S. Department of Energy's Brookhaven National Laboratory have shown that increasing the level of a brain protein important for transmitting pleasure signals can turn rats that prefer alcohol into light drinkers, and those with no preference into near teetotalers.

The findings, published in the first September 2001 issue (vol 78 (5)) of the Journal of Neurochemistry may have implications for the prevention and treatment of alcoholism in humans.

"This is a preliminary study, but when you see a rat that chooses to drink 80% to 90% of its daily fluid as alcohol, and then three days later it's down to 20%, that's a dramatic drop...

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Source: Gene Therapy Weekly (2001-09-20)

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