Atherosclerosis

Coated Stent Transfers Genes, Drugs With Efficiency

Published in Gene Therapy Weekly, October 11th, 2001

by Sonia Nichols, senior medical writer - Members of a research team in Japan have developed a hydrogel coating for metallic stents that effectively delivers drugs or transfers genes to damaged arterial tissues.

The coating compound consists of a gelatinous substance combined with a photo-initiator called carboxylated camphorquinone, according to Yasuhide Nakayama, National Cardiovascular Center Research Institute, Japan, and coinvestigators.

"A few minutes of visible light irradiation of a stent after dip-coating of an aqueous solution of the photoreactive material resulted in the formation of a homogeneously crosslinked gelatinous layer on the...

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Source: Gene Therapy Weekly (2001-10-11)

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