Birth Defects

Treating Congenital Problems With Gene Therapy In Utero Believed Possible

Published in Gene Therapy Weekly, October 18th, 2001

by Sonia Nichols, senior medical writer - Scientists believe birth defects detected while a fetus is in utero could be treated with therapies incorporating transduced stem cells administered before birth or shortly thereafter.

However, first, researchers must optimize stem cell transduction. A team at the University of California at San Francisco recently reported their experiences with retroviral transduction using stem cells obtained from the livers of fetuses. Their results suggest that with the right culture conditions, transduced cells remain a viable method for delivering gene therapies targeting birth defects.

Stem cells obtained from the...

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Source: Gene Therapy Weekly (2001-10-18)

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