Human Reproduction

Sperm Antigen Might Be Good Contraception, Solve Reproductive Problems

Published in Gene Therapy Weekly, October 25th, 2001

by Sonia Nichols, senior medical writer - The new discovery of a cDNA fragment that encodes for sperm antigen could some day be used for developing methods that enhance human reproductive medicine.

Ramasamy Santhanam and a colleague at the Medical College of Ohio discovered a new cDNA fragment that codes for sperm antigen called TSA-1 after using testis-specific cDNA to screen a portion of the human gene library. Recombinant TSA-1 could eventually be used in a contraceptive vaccine or for screening men with infertility, according to Santhanam and coworkers

"The computer-generated translated protein has a calculated molecular mass of 17.4 kDa and...

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Source: Gene Therapy Weekly (2001-10-25)

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