Published in Gene Therapy Weekly, November 15th, 2001
As reported by Hal M. Hoffman, MD, and colleagues in the November 2001 edition of Nature Genetics, the protein, which they have named cryopyrin, is the likely culprit in two periodic fever syndromes: familial cold autoinflammatory syndrome (FCAS), in which affected people develop rashes and other symptoms when exposed to cold air, and Muckle-Wells syndrome (MWS), which causes deafness as well as periodic fevers.
Autoinflammatory conditions are those in which the body reacts as though it were being...
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