Functional Genomics

Scientists Construct Biomolecular Nanomachine

Published in Gene Therapy Weekly, December 13th, 2001

Researchers have built a computing machine that uses DNA as its software and enzymes as its hardware, according to a report in Nature.

Biomolecular nanomachines have a long way to go before they become practical, but they may one day find uses in screening libraries of DNA sequences, or even inside cells, where they could monitor conditions and synthesize drugs.

Computers whose input and output are strands of DNA have been devised before, but they have always required a laborious series of reactions, each needing human supervision. The automaton developed by Ehud Shapiro, of the Weizmann Institute, Rehovot, Israel, and colleagues requires...

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Source: Gene Therapy Weekly (2001-12-13)

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