Antiviral Therapy

Ribozymes May Hold The Key For Treating Hepatitis B, Virus-Related Cancer

Published in Gene Therapy Weekly, December 13th, 2001

by Sonia Nichols, senior medical writer - Gene therapy using catalytic forms of RNA, or ribozymes, may offer a way to treat patients with hepatitis B virus (HBV) infections that are resistant to conventional forms of therapy.

"Hammerhead ribozymes have recently gained attention as potential tools to inhibit viral infection, for which there are no general effective therapies available," Y. Feng and colleagues from the Chinese Academy of Sciences in China noted in a recent issue of the Journal of Gastroenterology and Hepatology.

Ribozymes can cut and even splice RNA chains. Feng and fellow researchers used hammerhead ribozymes (RZC) to disrupt...

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Source: Gene Therapy Weekly (2001-12-13)

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