Stroke

Scientists Have Identified 3-D Structure Of DAPK

Published in Gene Therapy Weekly, December 27th, 2001

Critical new data on a complex enzyme that lies at the crossroad between cell suicide and tumor suppression has opened a promising new front in the battle to find effective treatments for stroke and cancer.

Scientists at Vanderbilt University and Northwestern University have determined the three-dimensional structure of a critical region of death-associated protein kinase (DAPK) and created a quantitative assay capable of measuring its activity.

These results were published in the October 2001 issue of Nature Structural Biology and the October 19, 2001, issue of the Journal of Biological Chemistry and are generating considerable...

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Source: Gene Therapy Weekly (2001-12-27)

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