Published in Gene Therapy Weekly, December 27th, 2001
Simply put, nonviral gene transfer methods do not always work well, scientists say. Using a strategy called steroid-mediated gene delivery, however, Alexandre Rebuffat and colleagues at the University of Fribourg in Switzerland have taken advantage of cellular glucocorticoid receptors to ease genes into targeted cells. The description of their experiments was published in the December 2001 edition of Nature Biotechnology.
Rebuffat and coworkers studied a number of steroid...
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