Fetal Alcohol Syndrome

Research Hints At Genetic Protection Against FAS

Published in Gene Therapy Weekly, January 10th, 2002

Fetal alcohol syndrome (FAS) is the most common cause of preventable mental retardation among children in the world today, and now scientists believe that the development of FAS following excessive alcohol exposure is likely influenced by genetic factors in both the mother and child.

Mixed-ancestry children in the Western Cape Province of South Africa have the highest frequency of FAS in the world. Knowing that allelic variation influences alcohol metabolizing genes, researchers report in the December 2001 issue of Alcoholism: Clinical and Experimental Research what role polymorphisms of the alcohol dehydrogenase (ADH2) gene might have among this...

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Source: Gene Therapy Weekly (2002-01-10)

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