Brain Cancer

Cancer Gene Therapy Delivers IL-12 Directly To Glioma

Published in Gene Therapy Weekly, January 17th, 2002

The administration of interleukin 12 (IL-12) has been shown in previous animal studies to be an effective therapy in treating cancer. But while this cytokine plays a key role in enabling the immune system's T cells to attack cancer cells, systemic administration can cause harmful changes in blood and tissues, and other life-threatening side effects.

To take advantage of IL-12's benefits without risking the negative consequences, researchers seek IL-12 delivery methods that will attack cancer cells at the site of a tumor.

In an article appearing in the December 28, 2001, issue of Cancer Gene Therapy, physicians and scientists at Cedars-Sinai's...

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Source: Gene Therapy Weekly (2002-01-17)

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