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Steatohepatitis

Tumor Necrosis Factor Highly Expressed In Nonalcoholic Steatohepatitis

Published in Gene Therapy Weekly, January 24th, 2002

by Sonia Nichols, senior medical writer - The gene for an important cytokine is highly expressed in the tissues of patients with nonalcoholic steatohepatitis (NASH), suggesting the possibility of using targeted gene therapies for treating affected individuals.

NASH, also called nonalcoholic fatty liver disease, is a disease of the obese or diabetic, and can produce liver damage similar to that observed in people who consume too much alcohol. Liver fibrosis and liver cirrhosis sometimes becomes apparent in some but not all patients with NASH.

Researchers at the University Hospital of Marques de Valdecilla in Spain have compared adipose and liver...

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