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Depression

One Gene Underlies Bipolar Illness, Panic Disorder

Published in Gene Therapy Weekly, January 31st, 2002

The genetic underpinnings of panic disorder and manic-depressive (bipolar) illness have long eluded scientists.

Now, researchers at Johns Hopkins studying the inheritance patterns of these conditions have concluded that they probably are not separate diseases at all, but different forms of a shared and complex biological condition.

"We've shown that panic attacks and panic disorder are related genetically to bipolar disorder and therefore likely share a common cause," says Dean F. MacKinnon, MD, assistant professor of psychiatry at Hopkins and lead author of a report on the study in the January 2002 issue of the American Journal of Psychiatry....

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