Central Nervous System Disease

Neural Progenitor Cells Retain Ability to Differentiate After Transduction

Published in Gene Therapy Weekly, February 7th, 2002

by Sonia Nichols, senior medical writer - Neural progenitor cells, or stem cells, retain much of their ability to differentiate after virus-mediated transduction, researchers in the U.S. report.

Much has been made of the potential for treating humans with neurodegenerative diseases or injury to the central nervous system with embryonic stem cells. A group at the University of Iowa College of Medicine has looked at embryonic neural stem cells obtained from mice and determined such cells can be effectively transduced with gene therapy while at the same time retaining their ability to regenerate and differentiate into different types of nervous system cells.

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Source: Gene Therapy Weekly (2002-02-07)

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