Neurology

Vaccine Combination Rejects Brain Tumor Establishment In Rodents

Published in Gene Therapy Weekly, February 21st, 2002

by Sonia Nichols, senior medical writer - Using a combination of cytokine-based gene therapy and tumor cell vaccination, medical investigators have been able to produce immunity against brain tumors in rats.

The strategy of using a combination of therapies attempts to overcome previous problems seen in gene therapies meant for treating brain tumors, for it addresses the need for antigen presentation as well as sufficient immune cell recruitment, according to Y. Iwadate and associates at Chiba University Graduate School of Medicine in Japan.

"We investigated the therapeutic potential of induced systemic immunity in peripheral tissues combined with...

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Source: Gene Therapy Weekly (2002-02-21)

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