Cystic Fibrosis
Mini-proteins used to repair defect in model cell systems
Published in Gene Therapy Weekly, April 18th, 2002
Cystic fibrosis (CF) is caused by mutations in a gene that encodes the cystic fibrosis transmembrane regulator (CFTR) protein. Normal CFTR protein forms channels for chloride ions to leave cells. The controlled outflow of chloride ions maintains cells' electrolyte and fluid balance and allows bacteria to be cleared from the surface of airway cells. This action prevents infection, which is a leading cause of death in people with CF.
University of Iowa researchers have shown that shortened versions of the normal CFTR protein can function like the normal full-length protein in experimental models of CF disease. These findings may point the way toward strategies that...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2002-04-18)
More Articles from Gene Therapy Weekly
- Tissue Grafting
Thrombomodulin loss responsible for early problems after vein grafts - Transcription Repressors
Conjugated oligonucleotide overcomes uptake properties - Liver Disease
Herpes simplex virus and radiation cause regression in hepatoma - Melanoma
Differentiation gene may open new avenues for suppressing advanced cancer - Ovarian Cancer
Targeting serotype 3 receptor enhances gene transfer efficiency - Atherosclerosis
Lexicon Genetics discovers target for the development of drugs to treat heart disease - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
