Cancer Vaccine

Cells expressing interleukin-2 arrest cancer growth and boost tumor immunity

Published in Gene Therapy Weekly, May 23rd, 2002

by Sonia Nichols, senior medical writer - Fibroblasts genetically engineered to express interleukin (IL)-2 cause tumor cell growth inhibition and protect against the formation of new brain tumors.

Medical researchers at Rush Medical College in Chicago, Illinois, have used the cells to successfully treat murine models with established glioma and prevent cerebral breast cancer establishment, according to a report in the May 2002 issue of Cancer Gene Therapy.

Terry Lichtor and colleagues reported that as a result of treating mice with allogeneic/syngeneic fibroblasts expressing IL-2 who bore established, growing glioma tumors, survival was...

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Source: Gene Therapy Weekly (2002-05-23)

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